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Pierluigi Gambetti Selected Research

Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)

11/2019Role of prion protein glycosylation in replication of human prions by protein misfolding cyclic amplification.
1/2019PMCA-replicated PrPD in urine of vCJD patients maintains infectivity and strain characteristics of brain PrPD: Transmission study.
1/2018Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study.
6/2015Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone.
6/2015Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains.
12/2014Transmission characteristics of variably protease-sensitive prionopathy.
8/2014Prions in the urine of patients with variant Creutzfeldt-Jakob disease.
8/2014Comparative Study of Prions in Iatrogenic and Sporadic Creutzfeldt-Jakob Disease.
12/2013Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases.
7/2013Prions in variably protease-sensitive prionopathy: an update.
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Pierluigi Gambetti Research Topics

Disease

59Prion Diseases (Transmissible Spongiform Encephalopathies)
10/2022 - 09/2002
25Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
11/2019 - 03/2003
15Scrapie
01/2018 - 10/2003
13Sporadic Creutzfeldt-Jakob Disease
10/2021 - 04/2003
12Acquired CJD
11/2019 - 01/2003
8Neurodegenerative Diseases (Neurodegenerative Disease)
10/2020 - 10/2003
6Alzheimer Disease (Alzheimer's Disease)
01/2018 - 03/2003
6Infections
07/2013 - 12/2004
5Sleep Initiation and Maintenance Disorders (Insomnia)
07/2012 - 01/2003
5Fatal Familial Insomnia
03/2006 - 12/2002
3Frontotemporal Dementia (Semantic Dementia)
11/2014 - 02/2004
2Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
10/2020 - 09/2005
2Kuru
01/2020 - 06/2015
2Nervous System Diseases (Neurological Disorders)
11/2019 - 01/2017
2Bovine Spongiform Encephalopathy (Mad Cow Disease)
06/2015 - 04/2008
2Dementia (Dementias)
11/2011 - 06/2008
2Chronic Wasting Disease
03/2011 - 02/2006
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2018
1Proteostasis Deficiencies
02/2016
1Mitochondrial Diseases (Mitochondrial Disease)
10/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
08/2014
1Normal Pressure Hydrocephalus
11/2011
1Fibrosis (Cirrhosis)
04/2007
1Muscular Atrophy (Muscle Atrophy)
04/2007
1Muscular Diseases (Myopathy)
04/2007
1Dermatomyositis (Dermatopolymyositis)
04/2007
1Inclusion Body Myositis
04/2007
1Down Syndrome (Down's Syndrome)
01/2006
1Parkinson Disease (Parkinson's Disease)
09/2005
1HIV Infections (HIV Infection)
10/2004
1Amyloid Plaque
07/2004
1Sleep Wake Disorders
12/2002

Drug/Important Bio-Agent (IBA)

56Prion ProteinsIBA
10/2021 - 09/2002
38PrionsIBA
10/2020 - 03/2003
25Peptide Hydrolases (Proteases)FDA Link
10/2022 - 01/2003
20Codon (Codons)IBA
10/2021 - 12/2002
11Valine (L-Valine)FDA Link
10/2021 - 01/2005
10Proteins (Proteins, Gene)FDA Link
01/2019 - 03/2003
9Methionine (L-Methionine)FDA Link
10/2021 - 01/2005
9Endopeptidase K (Proteinase K)IBA
01/2018 - 10/2003
9Protein Isoforms (Isoforms)IBA
07/2013 - 03/2003
6PrPSc ProteinsIBA
01/2017 - 12/2004
5Amyloid beta-PeptidesIBA
10/2009 - 02/2004
4Amyloid (Amyloid Fibrils)IBA
01/2020 - 07/2004
3Biomarkers (Surrogate Marker)IBA
01/2019 - 12/2004
3Detergents (Detergent)IBA
05/2010 - 01/2005
2tau Proteins (tau Protein)IBA
10/2020 - 01/2017
2Growth Hormone (Somatotropin)IBA
01/2018 - 06/2015
2Glutamic Acid (Glutamate)FDA Link
12/2013 - 10/2004
2AntibodiesIBA
10/2009 - 11/2007
1SphingolipidsIBA
10/2020
1Polysaccharides (Glycans)IBA
11/2019
1thioflavin TIBA
01/2018
1Mitochondrial DNA (mtDNA)IBA
10/2015
1Glycine (Aminoacetic Acid)FDA LinkGeneric
12/2013
1Isoleucine (L-Isoleucine)FDA Link
07/2013
1BuffersIBA
05/2010
1SaltsIBA
05/2010
1Protein AggregatesIBA
11/2008
1Doxycycline (Periostat)FDA LinkGeneric
04/2007
1Glucose (Dextrose)FDA LinkGeneric
03/2006
1Deoxyglucose (2 Deoxy D glucose)IBA
03/2006
1Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA
01/2006
18-hydroxyguanosineIBA
09/2005
1Heme Oxygenase-1IBA
09/2005
1EpitopesIBA
01/2005
1EnzymesIBA
12/2004
1AntioxidantsIBA
10/2004
1Caspase 3 (Caspase-3)IBA
10/2004
1methionylmethionine (Met-Met)IBA
10/2004
1Interleukin-1 (Interleukin 1)IBA
10/2004
1Excitatory Amino AcidsIBA
10/2004
1HLA-DR Antigens (HLA-DR)IBA
10/2004
1Glutathione (Reduced Glutathione)IBA
10/2004
1LigandsIBA
07/2004
11,4- bis(4'- hydroxystyryl)- 2- methoxybenzeneIBA
07/2004
1Staphylococcal Protein A (Protein A)IBA
02/2004
1DNA (Deoxyribonucleic Acid)IBA
02/2004
1DNA-Binding Proteins (DNA Binding Protein)IBA
02/2004
1A-Form DNA (A-DNA)IBA
02/2004
1AS 8IBA
02/2004
1urinary gonadotropin fragmentIBA
10/2003
1GPI-Linked ProteinsIBA
12/2002

Therapy/Procedure

1Therapeutics
01/2005
1Intravenous Administration
07/2004